A -related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy
نویسندگان
چکیده
منابع مشابه
Abeta-related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy.
Idiopathic or primary angiitis of the CNS (PACNS) and cerebral amyloid angiopathy (CAA) are unusual vasculopathies generally regarded as unrelated disorders. A few case reports have, however, described granulomatous angiitis in patients with sporadic, amyloid beta peptide (Abeta)-related CAA. Here we describe the clinical, neuroradiological and neuropathological features of nine patients with A...
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C erebral amyloid angiopathy (CAA) results from depo-sition of amyloid-β fibrils in the wall of the small and medium-sized blood vessels, mostly arteries of the lepto-meninges and cerebral cortex. Architectural disruption of amyloid-β laden vessels, occasionally with fibrinoid necrosis, leads to perivascular leakage. Vascular rupture causes lobar microbleeds or hematomas and high-convexity suba...
متن کاملprimary angiitis of the central nervous system
primary angiitis of the central nervous system (pacns) is an idiopathic disorder (vasculitis) restricted to the central nervous system (cns). it often presents with focal neurological deficits suggesting stroke or a combination of confusion and headache. we herein report three cases with various combinations of fever, partial seizure, encephalopathy, paresis, headache and ataxia. one of them wa...
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Vascular inflammation is present in a subset of patients with cerebral amyloid angiopathy (CAA) and has a major influence in determining the disease manifestations. Radiological characterization of this subset is particularly important to achieve early recognition and treatment. We conducted this study to investigate the role of imaging in differentiating CAA with and without inflammation. We r...
متن کاملUveitis associated with Primary Angiitis of the Central Nervous System.
BACKGROUND In Primary Angiitis of the Central Nervous System (PACNS), disease is typically limited to the brain and spinal cord although other organs may be affected. Uveitis is occasionally seen in systemic vasculitides but is not a recognized manifestation of PACNS. We describe two patients who developed PACNS following the onset of uveitis. CASE DESCRIPTIONS Case 1--a 47-year-old male suff...
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ژورنال
عنوان ژورنال: Brain
سال: 2005
ISSN: 1460-2156
DOI: 10.1093/brain/awh379